Structural highlights
Function
VHLP_ASFB7 DNA-binding protein that plays a critical role in nucleoid compaction, genome replication and DNA replication and transcription (PubMed:28381576). Binds to both ssDNA and dsDNA with a binding site covering about 15 nucleotides (PubMed:28381576). Displays DNA-supercoiling activity only when associated with the viral DNA topoisomerase 2 (PubMed:28381576).[1]
References
- ↑ Frouco G, Freitas FB, Coelho J, Leitão A, Martins C, Ferreira F. DNA-Binding Properties of African Swine Fever Virus pA104R, a Histone-Like Protein Involved in Viral Replication and Transcription. J Virol. 2017 May 26;91(12):e02498-16. PMID:28381576 doi:10.1128/JVI.02498-16
