6lqq

From Proteopedia

Cryo-EM structure of 90S small subunit preribosomes in transition states (State B)

Structural highlights

6lqq is a 10 chain structure with sequence from Saccharomyces cerevisiae S288C. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	Electron Microscopy, Resolution 4.1Å
Ligands:	GTP, MG, ZN
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

UTP15_YEAST Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I together with a subset of U3 proteins required for transcription (t-UTPs).^[1] ^[2]

References

↑ Dragon F, Gallagher JE, Compagnone-Post PA, Mitchell BM, Porwancher KA, Wehner KA, Wormsley S, Settlage RE, Shabanowitz J, Osheim Y, Beyer AL, Hunt DF, Baserga SJ. A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis. Nature. 2002 Jun 27;417(6892):967-70. Epub 2002 Jun 9. PMID:12068309 doi:http://dx.doi.org/10.1038/nature00769
↑ Gallagher JE, Dunbar DA, Granneman S, Mitchell BM, Osheim Y, Beyer AL, Baserga SJ. RNA polymerase I transcription and pre-rRNA processing are linked by specific SSU processome components. Genes Dev. 2004 Oct 15;18(20):2506-17. PMID:15489292 doi:http://dx.doi.org/18/20/2506

1 Structural highlights
2 Function
3 See Also
4 References

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PDB ID 6lqq

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Categories: Large Structures | Saccharomyces cerevisiae S288C | Du Y | Ye K

6lqq

From Proteopedia

Cryo-EM structure of 90S small subunit preribosomes in transition states (State B)

Structural highlights

Function

See Also

References

Contents

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