6mgw

Structural highlights

Function

CSC1_ARATH Acts as an osmosensitive calcium-permeable cation channel. Specifically conducts cations including Ca(2+), K(+) and Na(+) in vitro. Inactivation or closure of the channel is calcium-dependent.^[1]

See Also

• Ion channels 3D structures

References

1. ↑ Hou C, Tian W, Kleist T, He K, Garcia V, Bai F, Hao Y, Luan S, Li L. DUF221 proteins are a family of osmosensitive calcium-permeable cation channels conserved across eukaryotes. Cell Res. 2014 May;24(5):632-5. doi: 10.1038/cr.2014.14. Epub 2014 Feb 7. PMID:24503647 doi:http://dx.doi.org/10.1038/cr.2014.14