6mgw

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Structure of mechanically activated ion channel OSCA1.2 in LMNG

Structural highlights

6mgw is a 2 chain structure with sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Electron Microscopy, Resolution 3.5Å
Experimental data:Check to display Experimental Data
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CSC1_ARATH Acts as an osmosensitive calcium-permeable cation channel. Specifically conducts cations including Ca(2+), K(+) and Na(+) in vitro. Inactivation or closure of the channel is calcium-dependent.[1]

See Also

References

  1. ↑ Hou C, Tian W, Kleist T, He K, Garcia V, Bai F, Hao Y, Luan S, Li L. DUF221 proteins are a family of osmosensitive calcium-permeable cation channels conserved across eukaryotes. Cell Res. 2014 May;24(5):632-5. doi: 10.1038/cr.2014.14. Epub 2014 Feb 7. PMID:24503647 doi:http://dx.doi.org/10.1038/cr.2014.14

Contents


6mgw, resolution 3.50Å

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