6qay

Structural highlights

Function

TAPA_BACSU Required for biofilm formation (PubMed:16430695, PubMed:16430696, PubMed:21477127, PubMed:24488317). Required for the proper anchoring and polymerization of TasA amyloid fibers at the cell surface (PubMed:16430696, PubMed:21477127, PubMed:24488317). Is also a minor component of TasA fibers (PubMed:21477127).^{[1] [2] [3] [4]}

References

1. ↑ Chu F, Kearns DB, Branda SS, Kolter R, Losick R. Targets of the master regulator of biofilm formation in Bacillus subtilis. Mol Microbiol. 2006 Feb;59(4):1216-28. doi: 10.1111/j.1365-2958.2005.05019.x. PMID:16430695 doi:http://dx.doi.org/10.1111/j.1365-2958.2005.05019.x
2. ↑ Branda SS, Chu F, Kearns DB, Losick R, Kolter R. A major protein component of the Bacillus subtilis biofilm matrix. Mol Microbiol. 2006 Feb;59(4):1229-38. doi: 10.1111/j.1365-2958.2005.05020.x. PMID:16430696 doi:http://dx.doi.org/10.1111/j.1365-2958.2005.05020.x
3. ↑ Romero D, Vlamakis H, Losick R, Kolter R. An accessory protein required for anchoring and assembly of amyloid fibres in B. subtilis biofilms. Mol Microbiol. 2011 Jun;80(5):1155-68. doi: 10.1111/j.1365-2958.2011.07653.x., Epub 2011 May 5. PMID:21477127 doi:http://dx.doi.org/10.1111/j.1365-2958.2011.07653.x
4. ↑ Romero D, Vlamakis H, Losick R, Kolter R. Functional analysis of the accessory protein TapA in Bacillus subtilis amyloid fiber assembly. J Bacteriol. 2014 Apr;196(8):1505-13. doi: 10.1128/JB.01363-13. Epub 2014 Jan 31. PMID:24488317 doi:http://dx.doi.org/10.1128/JB.01363-13