Structural highlights
Function
NPR4_ARATH May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Involved in the regulation of basal defense responses against pathogens, and may be implicated in the cross-talk between the SA- and JA-dependent signaling pathways.[1] [2]
References
- ↑ Liu G, Holub EB, Alonso JM, Ecker JR, Fobert PR. An Arabidopsis NPR1-like gene, NPR4, is required for disease resistance. Plant J. 2005 Jan;41(2):304-18. doi: 10.1111/j.1365-313X.2004.02296.x. PMID:15634206 doi:http://dx.doi.org/10.1111/j.1365-313X.2004.02296.x
- ↑ Zhang Y, Cheng YT, Qu N, Zhao Q, Bi D, Li X. Negative regulation of defense responses in Arabidopsis by two NPR1 paralogs. Plant J. 2006 Dec;48(5):647-56. doi: 10.1111/j.1365-313X.2006.02903.x. Epub 2006 , Oct 31. PMID:17076807 doi:http://dx.doi.org/10.1111/j.1365-313X.2006.02903.x
