7bwd

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Structure of Dot1L-H2BK34ub Nucleosome Complex

Structural highlights

7bwd is a 13 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Electron Microscopy, Resolution 4.32Å
Ligands:SAH
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

DOT1L_HUMAN Histone methyltransferase. Methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones. Binds to DNA.

See Also

Contents


PDB ID 7bwd

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OCA

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