7c7a

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Cryo-EM structure of yeast Ribonuclease MRP with substrate ITS1

Structural highlights

7c7a is a 11 chain structure with sequence from Saccharomyces cerevisiae S288C. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Electron Microscopy, Resolution 2.8Å
Ligands:MG, ZN
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

POP1_YEAST Required for processing of 5.8S rRNA (short form) at site A3 and for 5' and 3' processing of pre-tRNA.[1] [2]

See Also

References

  1. Lygerou Z, Mitchell P, Petfalski E, Seraphin B, Tollervey D. The POP1 gene encodes a protein component common to the RNase MRP and RNase P ribonucleoproteins. Genes Dev. 1994 Jun 15;8(12):1423-33. PMID:7926742
  2. Chamberlain JR, Lee Y, Lane WS, Engelke DR. Purification and characterization of the nuclear RNase P holoenzyme complex reveals extensive subunit overlap with RNase MRP. Genes Dev. 1998 Jun 1;12(11):1678-90. PMID:9620854

Contents


PDB ID 7c7a

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