7kzp

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Structure of the human Fanconi anaemia Core complex

Structural highlights

7kzp is a 14 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Electron Microscopy, Resolution 3.1Å
Ligands:ZN
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Disease

FANCA_HUMAN Fanconi anemia. The disease is caused by variants affecting the gene represented in this entry.

Function

FANCA_HUMAN DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be involved in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability.

Contents


PDB ID 7kzp

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OCA

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