7oa5

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RUVA COMPLEXED TO A HOLLIDAY JUNCTION.

Structural highlights

7oa5 is a 12 chain structure with sequence from Mycobacterium leprae and Mycobacterium leprae TN. This structure supersedes the now removed PDB entry 1bvs. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.378Å
Ligands:CA
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RUVA_MYCLE The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity).

See Also

Contents


PDB ID 7oa5

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OCA

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