Structural highlights
Function
MABO2_PAENI Catalyzes the removal of methylamine from 4-methylaminobutanoate with the formation of succinate semialdehyde. Is involved in the catabolism of 4-methylaminobutanoate produced from nicotine. Has a very weak monoamine oxidase activity with 4-aminobutanoate. Cannot use spermidine, spermine, sarcosine, dimethylglycine, glycine, choline, betaine, alpha-methylamino isobutyrate, methylamine propionitrile and methylamino propylamine as substrate.[1]
References
- ↑ Chiribau CB, Mihasan M, Ganas P, Igloi GL, Artenie V, Brandsch R. Final steps in the catabolism of nicotine. FEBS J. 2006 Apr;273(7):1528-36. PMID:16689938 doi:10.1111/j.1742-4658.2006.05173.x
