7ssz

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Structure of human Kv1.3 with A0194009G09 nanobodies

Structural highlights

7ssz is a 8 chain structure with sequence from Aequorea victoria, Homo sapiens and Synthetic construct. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:K
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[KCNA3_HUMAN] Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.[GFP_AEQVI] Energy-transfer acceptor. Its role is to transduce the blue chemiluminescence of the protein aequorin into green fluorescent light by energy transfer. Fluoresces in vivo upon receiving energy from the Ca(2+)-activated photoprotein aequorin.

Contents


PDB ID 7ssz

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OCA

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