7suk

Structural highlights

Function

MPP10_YEAST Involved in nucleolar processing of pre-18S ribosomal RNA. Required for the early cleavages at sites A0, A1 and A2 during 18S ribosomal pre-RNA processing.^{[1] [2]}

References

1. ↑ Gerczei T, Correll CC. Imp3p and Imp4p mediate formation of essential U3-precursor rRNA (pre-rRNA) duplexes, possibly to recruit the small subunit processome to the pre-rRNA. Proc Natl Acad Sci U S A. 2004 Oct 26;101(43):15301-6. Epub 2004 Oct 15. PMID:15489263 doi:http://dx.doi.org/10.1073/pnas.0406819101
2. ↑ Dunbar DA, Wormsley S, Agentis TM, Baserga SJ. Mpp10p, a U3 small nucleolar ribonucleoprotein component required for pre-18S rRNA processing in yeast. Mol Cell Biol. 1997 Oct;17(10):5803-12. PMID:9315638