Structural highlights
Function
G0S0T5_CHATD VPS13_CHATD Mediates the transfer of lipids between membranes at organelle contact sites (By similarity). Binds phospholipids, including phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidic acid (PA), and phosphatidylserine (PS) (PubMed:30093493). May play a role in mitochondrial lipid homeostasis, Golgi vesicle transport, reticulophagy, actin cytoskeleton organization and formation of the prospore membrane (By similarity).[UniProtKB:Q07878][1]
References
- ↑ Kumar N, Leonzino M, Hancock-Cerutti W, Horenkamp FA, Li P, Lees JA, Wheeler H, Reinisch KM, De Camilli P. VPS13A and VPS13C are lipid transport proteins differentially localized at ER contact sites. J Cell Biol. 2018 Oct 1;217(10):3625-3639. doi: 10.1083/jcb.201807019. Epub 2018 , Aug 9. PMID:30093493 doi:http://dx.doi.org/10.1083/jcb.201807019
