8cix

From Proteopedia

DNA-polymerase sliding clamp (DnaN) from Escherichia coli in complex with Griselimycin.

Structural highlights

8cix is a 2 chain structure with sequence from Escherichia coli and Streptomyces griseus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 1.76Å
Ligands:	ACE, ACT, CA, GOL, MG, MLU, MP8, MVA, NA, NZC
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

DPO3B_ECOLI DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA.

1 Structural highlights
2 Function

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PDB ID 8cix

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8cix

From Proteopedia

DNA-polymerase sliding clamp (DnaN) from Escherichia coli in complex with Griselimycin.

Structural highlights

Function

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