8f9b

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Compound 19 bound to procaspase-6

Structural highlights

8f9b is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.65Å
Ligands:XN5
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CASP6_HUMAN Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.

Contents


PDB ID 8f9b

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OCA

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