8frx

From Proteopedia

Jump to: navigation, search

Full-length mouse 5-HT3A receptor in complex with SMP100, pre-activated

Structural highlights

8frx is a 5 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Electron Microscopy, Resolution 2.7Å
Ligands:NAG, Y82
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

5HT3A_MOUSE This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel.

Contents


PDB ID 8frx

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://proteopedia.org/wiki/index.php/8frx"
Personal tools