8xzf

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Cryo-EM structure of the WN561-bound human APLNR-Gi complex

Structural highlights

8xzf is a 6 chain structure with sequence from Homo sapiens and Synthetic construct. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Electron Microscopy, Resolution 3Å
Ligands:MED
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

APJ_HUMAN Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity. Alternative coreceptor with CD4 for HIV-1 infection; may be involved in the development of AIDS dementia.

Contents


PDB ID 8xzf

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OCA

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