Structural highlights
Function
PIEZ1_CAEEL Pore-forming subunit of a mechanosensitive non-specific cation channel (By similarity). Generates currents characterized by a linear current-voltage relationship (By similarity). Plays a role in reproduction by positively regulating inter-tissue signaling to promote oocyte maturation, ovulation and fertilization, and sperm navigation from and to the spermatheca (PubMed:32490809). May play a role in regulating cytosolic and endoplasmic reticulum calcium ion release (PubMed:32490809).[UniProtKB:Q92508][1]
References
- ↑ Bai X, Bouffard J, Lord A, Brugman K, Sternberg PW, Cram EJ, Golden A. Caenorhabditis elegans PIEZO channel coordinates multiple reproductive tissues to govern ovulation. Elife. 2020 Jun 3;9:e53603. doi: 10.7554/eLife.53603. PMID:32490809 doi:http://dx.doi.org/10.7554/eLife.53603
