Function
Ankyrin repeat domain-containing protein (ARDCP) recruits kinesin to the cell cortex in order to control microtubule growth via its ankyrin domain[1].
Disease
Mutations in ARDCP 3 manifest as Bartsocas-Papas syndrome, a genetic disorder characterized by severe craniofacial and limb abnormalities[2].
Structural highlights
The 3D structure of the complex between human ARDCP 25 C-terminal and a kinesin peptide shows 2 types of interactions. Kinesin residues and residues [1]. .
3D structures of ankyrin repeat domain-containing protein
Ankyrin repeat domain-containing protein 3D structures
