Bicalutamide

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References

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 1.9 Helsen C, Van den Broeck T, Voet A, Prekovic S, Van Poppel H, Joniau S, Claessens F. Androgen receptor antagonists for prostate cancer therapy. Endocr Relat Cancer. 2014 Aug;21(4):T105-18. doi: 10.1530/ERC-13-0545. Epub 2014 , Mar 17. PMID:24639562 doi:http://dx.doi.org/10.1530/ERC-13-0545
  2. 2.0 2.1 2.2 Gao W, Kim J, Dalton JT. Pharmacokinetics and pharmacodynamics of nonsteroidal androgen receptor ligands. Pharm Res. 2006 Aug;23(8):1641-58. doi: 10.1007/s11095-006-9024-3. PMID:16841196 doi:http://dx.doi.org/10.1007/s11095-006-9024-3
  3. 3.0 3.1 3.2 Bohl CE, Gao W, Miller DD, Bell CE, Dalton JT. Structural basis for antagonism and resistance of bicalutamide in prostate cancer. Proc Natl Acad Sci U S A. 2005 Apr 26;102(17):6201-6. Epub 2005 Apr 15. PMID:15833816
  4. 4.0 4.1 Leone G, Tucci M, Buttigliero C, Zichi C, Pignataro D, Bironzo P, Vignani F, Scagliotti GV, Di Maio M. Antiandrogen withdrawal syndrome (AAWS) in the treatment of patients with prostate cancer. Endocr Relat Cancer. 2018 Jan;25(1):R1-R9. doi: 10.1530/ERC-17-0355. Epub 2017 , Sep 28. PMID:28971898 doi:http://dx.doi.org/10.1530/ERC-17-0355
  5. 5.0 5.1 5.2 5.3 5.4 5.5 5.6 5.7 5.8 5.9 Cavaliere F, Cozzini P. An insight about the mechanism of action (MoA) of R-bicalutamide on the androgen receptor homodimer using molecular dynamic. Toxicol Appl Pharmacol. 2022 Apr 1;440:115953. doi: 10.1016/j.taap.2022.115953. , Epub 2022 Mar 1. PMID:35245614 doi:http://dx.doi.org/10.1016/j.taap.2022.115953
  6. 6.0 6.1 Masiello D, Cheng S, Bubley GJ, Lu ML, Balk SP. Bicalutamide functions as an androgen receptor antagonist by assembly of a transcriptionally inactive receptor. J Biol Chem. 2002 Jul 19;277(29):26321-6. doi: 10.1074/jbc.M203310200. Epub 2002 , May 15. PMID:12015321 doi:http://dx.doi.org/10.1074/jbc.M203310200
  7. Duke CB, Jones A, Bohl CE, Dalton JT, Miller DD. Unexpected Binding Orientation of Bulky-B-Ring Anti-Androgens and Implications for Future Drug Targets. J Med Chem. 2011 Apr 20. PMID:21506597 doi:10.1021/jm2000097
  8. 8.0 8.1 Fujita K, Nonomura N. Role of Androgen Receptor in Prostate Cancer: A Review. World J Mens Health. 2019 Sep;37(3):288-295. doi: 10.5534/wjmh.180040. Epub 2018 , Sep 10. PMID:30209899 doi:http://dx.doi.org/10.5534/wjmh.180040
  9. Smith MR, Saad F, Chowdhury S, Oudard S, Hadaschik BA, Graff JN, Olmos D, Mainwaring PN, Lee JY, Uemura H, Lopez-Gitlitz A, Trudel GC, Espina BM, Shu Y, Park YC, Rackoff WR, Yu MK, Small EJ. Apalutamide Treatment and Metastasis-free Survival in Prostate Cancer. N Engl J Med. 2018 Apr 12;378(15):1408-1418. doi: 10.1056/NEJMoa1715546. Epub , 2018 Feb 8. PMID:29420164 doi:http://dx.doi.org/10.1056/NEJMoa1715546
  10. Pollock Y, Smith MR, Saad F, Chowdhury S, Oudard S, Hadaschik B, Olmos D, Lee JY, Uemura H, Bhaumik A, Londhe A, Rooney B, Brookman-May SD, De Porre P, Mundle SD, Small EJ. Clinical characteristics associated with falls in patients with non-metastatic castration-resistant prostate cancer treated with apalutamide. Prostate Cancer Prostatic Dis. 2022 Oct 8. doi: 10.1038/s41391-022-00592-9. PMID:36209239 doi:http://dx.doi.org/10.1038/s41391-022-00592-9

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