CRISPR subtype I-A

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Cas6 complex with RNA (PDB code 4ill)


  1. Shao Y, Li H. Recognition and Cleavage of a Nonstructured CRISPR RNA by Its Processing Endoribonuclease Cas6. Structure. 2013 Feb 27. pii: S0969-2126(13)00017-8. doi:, 10.1016/j.str.2013.01.010. PMID:23454186 doi:
  2. Wang R, Zheng H, Preamplume G, Shao Y, Li H. The impact of CRISPR repeat sequence on structures of a Cas6 protein-RNA complex. Protein Sci. 2012 Mar;21(3):405-17. doi: 10.1002/pro.2028. Epub 2012 Feb 9. PMID:22238224 doi:
  3. Reeks J, Sokolowski RD, Graham S, Liu H, Naismith JH, White MF. Structure of a dimeric crenarchaeal Cas6 enzyme with an atypical active site for CRISPR RNA processing. Biochem J. 2013 Mar 25. PMID:23527601 doi:10.1042/BJ20130269

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