Canine parvovirus

From Proteopedia

Function The DNA-containing capsid of canine parvovirus (CPV) contains 60 copies of the capsid protein related by icosahedral symmetry. See also Viral capsids. Disease The virus causes the parvo disease in dogs which is fatal if untreated. Structural highlights Each capsid protein participates in formation of 5-fold and 23-fold symmetry. Click here to see morph explaining this. Based on PDB entry 4dpv[1].

spinqualitylabelsall models Parvovirus coat protein complex with DNA (pink) and Mg+2 ions (green) (PDB code 4dpv) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

3D structures of canine parvovirus

Updated on 13-November-2022

2cas, 1c8d, 1c8h – Empty capsid protein 2
7m3m, 7m3o - capsid protein 2 – Cryo EM
3jcx, 7m3l, 7m3n - capsid protein 2 + antibody – Cryo EM
4qyk - variant
6oas - Vp1 - Cryo EM
1p5y, 1p5w – Vp2
1ijs, 4dpv – Protein 2 + DNA

References

1. ↑ Xie Q, Chapman MS. Canine parvovirus capsid structure, analyzed at 2.9 A resolution. J Mol Biol. 1996 Dec 6;264(3):497-520. PMID:8969301 doi:10.1006/jmbi.1996.0657