Catenin

Function

Catenins (CTN) are proteins which make complexes with cadherin.^[1]

• α-CTN links cadherin (CDH) and α-actinin, it is encoded by 3 genes: α-E-CTN (epithelial), α-T-CTN (membrane bound), and α-N-CTN (neuronal).
  
• β-CTN is a subunit of the cadherin complex. It contains Armadillo repeats which are a pair of helices forming hairpin structure.
  
• γ-CTN (or plakoglobin) is a component of desmosomes and contains armadillo repeats.
  
• δ-CTN is expressed in the brain and contains 10 armadillo repeats.
  
• p120 CTN is another member of the CTN family.
  

3D Structures of Catenin

Catenin 3D structures