Cytidine monophosphate kinase

spinqualitylabelsall models Structure of E. coli cytidine monophosphate kinase complex with CMP (PDB entry 1kdo) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Cytidine monophosphate kinase or cytidylate kinase (CMK) catalyzes the reversible conversion of CMP and ATP to CDP and ADP. Relevance CMK from bacterial pathogens is a target for new antibiotics development. Structural highlights CMK active site is highly sugar-specific. Water molecules are shown as red spheres.

3D structures of cytidine monophosphate kinase

(Updated on 16-June-2021)

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• CMK
  • 1tev – CMK – human
    
  • 1cke – EcCMK – Escherichia coli
    
  • 2fem – EcCMK (mutant)
    
  • 1q3t – CMK – Streptococcus pneumoniae
    
  • 3r8c – MaCMK – Mycobacterium abscessus
    
  • 3r20 – CMK – Mycobacterium smegmatis
    
  • 4e22 – CMK – Yersinia pseudotuberculosis
    
  • 3w90 – TtCMK – Thermus thermophilus
    
• CMK complex with ligand
  • 2cmk – EcCMK + CDP
    
  • 3akd – TtCMK + CDP
    
  • 7ckj, 3w8n – TtCMK + CMP
    
  • 4die – MaCMK + CMP
    
  • 1kdo – EcCMK + CMP
    
  • 1kdp – EcCMK + dCMP
    
  • 2feo – EcCMK (mutant) + dCMP
    
  • 1kdr – EcCMK + ara-CMP
    
  • 1kdt – EcCMK + ddCMP
    
  • 2h92 – CMK + CMP – Staphylococcus aureus
    
  • 7ckj – TtCMK + CMP
    
  • 3akc – TtCMK + CDP + ADP
    
  • 7l4a – CMK + CDP – Encephalitozoon cuniculi
    

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