Flavodoxin

Flavodoxin (FDX) is a bacterial protein which contains flavin mononucleotide (FMN) or flavin adenine dinucleotide (FAD). It participates in nitrogen metabolism and reduces N₂ to NH₃ while changing from its oxidized quinone state FDX-ox via semiquinone FDX-sq to its reduced hydroquinone state FDX-red^[1]. NrdI is a FDX which is involved in ribonucleotide reduction. WrbA (Tryptophan Repressor-Binding Protein) is also FDX. In E. coli there are 2 distinct flavodoxins: FDX I and II.

• Apo-Flavodoxin from Helicobacter pylori complexed with benzamidine and chloride ion.
• Cl coordination site. Water molecules shown as red spheres.

3D Structures of Flavodoxin

Flavodoxin 3D structures