Focal adhesion kinase

From Proteopedia

Jump to: navigation, search

Focal adhesion kinase 1 kinase domain complex with pyrimidine derivative inhibitor and sulfate (PDB code 2jkk)

Drag the structure with the mouse to rotate

References

  1. Mitra SK, Hanson DA, Schlaepfer DD. Focal adhesion kinase: in command and control of cell motility. Nat Rev Mol Cell Biol. 2005 Jan;6(1):56-68. PMID:15688067 doi:http://dx.doi.org/10.1038/nrm1549
  2. Cabrita MA, Jones LM, Quizi JL, Sabourin LA, McKay BC, Addison CL. Focal adhesion kinase inhibitors are potent anti-angiogenic agents. Mol Oncol. 2011 Dec;5(6):517-26. doi: 10.1016/j.molonc.2011.10.004. Epub 2011 Oct, 20. PMID:22075057 doi:http://dx.doi.org/10.1016/j.molonc.2011.10.004
  3. Lietha D, Eck MJ. Crystal structures of the FAK kinase in complex with TAE226 and related bis-anilino pyrimidine inhibitors reveal a helical DFG conformation. PLoS ONE. 2008;3(11):e3800. Epub 2008 Nov 24. PMID:19030106 doi:10.1371/journal.pone.0003800

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

Personal tools