Glucose-dependent Insulinotropic Polypeptide Receptor

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3D structures of GIPR

Updated on 08-August-2021

7dty – hGDIPR (mutant) + gastric inhibitory polypeptide + guanine nucleotide-binding protein + nanobody – human – Cryo EM
2qkh - hGDIPR extracellular domain 29-138 + GIP
4hj0, 6dkj - hGDIPR extracellular domain + antibody
6o9h, 6o9i - mGDIPR extracellular domain + antibody - mouse


  1. Lynn FC, Thompson SA, Pospisilik JA, Ehses JA, Hinke SA, Pamir N, McIntosh CH, Pederson RA. A novel pathway for regulation of glucose-dependent insulinotropic polypeptide (GIP) receptor expression in beta cells. FASEB J. 2003 Jan;17(1):91-3. Epub 2002 Nov 15. PMID:12475913 doi:10.1096/fj.02-0243fje
  2. Lynn FC, Pamir N, Ng EH, McIntosh CH, Kieffer TJ, Pederson RA. Defective glucose-dependent insulinotropic polypeptide receptor expression in diabetic fatty Zucker rats. Diabetes. 2001 May;50(5):1004-11. PMID:11334402
  3. "Byetta." BYETTA (exenatide) Injection | Welcome to Amylin Pharmaceuticals, Inc., 2011. Web. 02 Dec. 2011. <>

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