Histamine H1 receptor

From Proteopedia

Jump to: navigation, search

Histamine H1 Receptor

Histamine H1 receptor with an antagonist doxepin, lipid and phosphate (PDB code 3rze)

Drag the structure with the mouse to rotate

3D structures of histamine H1 receptor

Updated on 09-April-2023

3rze - hHHR + doxepin + lipid + phosphate - human
7dfl - hHHR + guanine nucleotide-binding protein + scFv + histamine - Cryo EM


  1. Shimamura T, Shiroishi M, Weyand S, Tsujimoto H, Winter G, Katritch V, Abagyan R, Cherezov V, Liu W, Han GW, Kobayashi T, Stevens RC, Iwata S. Structure of the human histamine H1 receptor complex with doxepin. Nature. 2011 Jun 22;475(7354):65-70. doi: 10.1038/nature10236. PMID:21697825 doi:10.1038/nature10236
  2. Richelson E. Tricyclic antidepressants and histamine H1 receptors. Mayo Clin Proc. 1979 Oct;54(10):669-74. PMID:39202
  3. Rovati GE, Capra V, Neubig RR. The highly conserved DRY motif of class A G protein-coupled receptors: beyond the ground state. Mol Pharmacol. 2007 Apr;71(4):959-64. doi: 10.1124/mol.106.029470. Epub 2006 Dec , 27. PMID:17192495 doi:http://dx.doi.org/10.1124/mol.106.029470

Proteopedia Page Contributors and Editors (what is this?)

Ann Taylor, Michal Harel, Alexander Berchansky

Personal tools