Human Fab PG16

From Proteopedia

Jump to: navigation, search

PDB ID 3mug

Drag the structure with the mouse to rotate


  1. 1.0 1.1 Robert Pejchal, Laura M. Walker, Robyn L. Stanfield, Sanjay K. Phogat, Wayne C. Koff, Pascal Poignard,Dennis R. Burton, and Ian A. Wilson. Structure and function of broadly reactive antibody PG16 reveal an H3 subdomain that mediates potent neutralization of HIV-1. Proc Natl Acad Sci U S A. 2010 June 22; 107(25): 11483–11488. PMCID: PMC2895122.
  2. Al-Lazikani B, Lesk AM, Chothia C. Standard conformations for the canonical structures of immunoglobulins. J Mol Biol. 1997 Nov 7;273(4):927-48. PMID:9367782 doi:10.1006/jmbi.1997.1354
  3. 3.0 3.1 3.2 Pancera M, McLellan JS, Wu X, Zhu J, Changela A, Schmidt SD, Yang Y, Zhou T, Phogat S, Mascola JR, Kwong PD. Crystal structure of PG16 and chimeric dissection with somatically related PG9: structure-function analysis of two quaternary-specific antibodies that effectively neutralize HIV-1. J Virol. 2010 Aug;84(16):8098-110. Epub 2010 Jun 10. PMID:20538861 doi:10.1128/JVI.00966-10

Created with the participation of Duncan Renfrow-Symon, David Canner.

Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky

Personal tools