Human Insulin Degrading Enzyme (Hebrew)

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6b7y אנזים מפרק האינסולין - דימר המורכב משתי מונומרים.

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1. Affholter JA, Fried VA, Roth RA (December 1988). "Human insulin-degrading enzyme shares structural and functional homologies with E. coli protease III". Science. 242 (4884): 1415–8.

2. Farris W, Mansourian S, Chang Y, Lindsley L, Eckman EA, Frosch MP, et al. (April 2003). "Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo". Proceedings of the National Academy of Sciences of the United States of America. 100 (7): 4162–7.

3. Hulse RE, Ralant LA, Tang WJ (February 2009). "Structure, Function, and Regulation of Insulin-Degrading Enzyme". Vitamins & Hormones 80:635-48. doi: 10.1016/S0083-6729(08)00622-5

4. Kerr ML, Small DH (April 2005). "Cytoplasmic domain of the beta-amyloid protein precursor of Alzheimer's disease: function, regulation of proteolysis, and implications for drug development". Journal of Neuroscience Research. 80 (2): 151–9. doi:10.1002/jnr.20408. PMID 15672415.

5. Kurochkin IV, Goto S (May 1994). "Alzheimer's beta-amyloid peptide specifically interacts with and is degraded by insulin degrading enzyme". FEBS Letters. 345 (1): 33–7. doi:10.1016/0014-5793(94)00387-4. PMID 8194595.

6. Mirsky IA, Broh-Kahn RH (January 1949). "The inactivation of insulin by tissue extracts; the distribution and properties of insulin inactivating extracts". Archives of Biochemistry. 20 (1): 1–9. PMID 18104389.

7.Wang DS, Dickson DW, Malter JS (2006). "beta-Amyloid degradation and Alzheimer's disease". Journal of Biomedicine & Biotechnology. 2006 (3): 58406. doi:10.1155/JBB/2006/58406. PMC 1559921. PMID 17047308.


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