Hypocretin and receptors

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Hypocretin and Receptors

NMR structure of orexin-b (PDB code 1cq0)


  1. 1.0 1.1 1.2 1.3 1.4 Latifi, B., Adamantidis, A., Bassetti, C., & Schmidt, M. H. (2018). Sleep-Wake Cycling and Energy Conservation: Role of Hypocretin and the Lateral Hypothalamus in Dynamic State-Dependent Resource Optimization. Frontiers in Neurology, 9. doi:10.3389/fneur.2018.00790
  2. 2.0 2.1 2.2 2.3 2.4 Suno, R., Kimura, K. T., Nakane, T., Yamashita, K., Wang, J., Fujiwara, T., … Kobayashi, T. (2018). Article: Crystal Structures of Human Orexin 2 Receptor Bound to the Subtype-Selective Antagonist EMPA. Structure, 26, 7–19.e5. https://doi.org/10.1016/j.str.2017.11.005
  3. 3.0 3.1 Kukkonen, J. P., & Leonard, C. S. (2013). Orexin/hypocretin receptor signalling cascades. British Journal of Pharmacology, 171(2), 314-331. doi:10.1111/bph.12324

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