Igf1 - alec

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Human insulin-like growth factor I complex with dodecyldimethylammonio-propanesulfonate (PDB code 1gzy)

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  1. Clemmons DR. Metabolic actions of insulin-like growth factor-I in normal physiology and diabetes. Endocrinol Metab Clin North Am. 2012 Jun;41(2):425-43, vii-viii. doi:, 10.1016/j.ecl.2012.04.017. PMID:22682639 doi:http://dx.doi.org/10.1016/j.ecl.2012.04.017
  2. 2.0 2.1 Laron Z. Insulin-like growth factor 1 (IGF-1): a growth hormone. Mol Pathol. 2001 Oct;54(5):311-6. PMID:11577173
  3. Phanse-Gupte SR, Khadilkar VV, Khadilkar AV. Clinical features and endocrine profile of Laron syndrome in Indian children. Indian J Endocrinol Metab. 2014 Nov;18(6):863-7. doi: 10.4103/2230-8210.140236. PMID:25364685 doi:http://dx.doi.org/10.4103/2230-8210.140236
  4. Velloso CP. Regulation of muscle mass by growth hormone and IGF-I. Br J Pharmacol. 2008 Jun;154(3):557-68. doi: 10.1038/bjp.2008.153. PMID:18500379 doi:http://dx.doi.org/10.1038/bjp.2008.153
  5. Levine ME, Suarez JA, Brandhorst S, Balasubramanian P, Cheng CW, Madia F, Fontana L, Mirisola MG, Guevara-Aguirre J, Wan J, Passarino G, Kennedy BK, Wei M, Cohen P, Crimmins EM, Longo VD. Low protein intake is associated with a major reduction in IGF-1, cancer, and overall mortality in the 65 and younger but not older population. Cell Metab. 2014 Mar 4;19(3):407-17. doi: 10.1016/j.cmet.2014.02.006. PMID:24606898 doi:http://dx.doi.org/10.1016/j.cmet.2014.02.006
  6. Braverman ER, Bowirrat A, Damle UJ, Yeldandi S, Chen TJ, Madigan M, Kerner M, Huang SX, Savarimuthu S, Blum K. Adult growth hormone deficiency treatment with a combination of growth hormone and insulin-like growth factor-1 resulting in elevated sustainable insulin-like growth factor-1 and insulin-like growth factor binding protein 3 plasma levels: a case report. J Med Case Rep. 2010 Sep 15;4:305. doi: 10.1186/1752-1947-4-305. PMID:20843352 doi:http://dx.doi.org/10.1186/1752-1947-4-305
  7. Holt RI, Sonksen PH. Growth hormone, IGF-I and insulin and their abuse in sport. Br J Pharmacol. 2008 Jun;154(3):542-56. doi: 10.1038/bjp.2008.99. Epub 2008 Mar, 31. PMID:18376417 doi:http://dx.doi.org/10.1038/bjp.2008.99

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Alec Nelson Kemp, Michal Harel, Alexander Berchansky

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