Image:PtGPX5 mechanism with cys44+cys92 disulfide EJJ 5-3-2022.png

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PtGPX5 mechanism. First, Cys44 of α1-helix scavenges the peroxide, and the helix locally twists and unfolds slightly to do this. This forms the Cys44-SOH sulfenic acid intermediate. Then, α2-helix completely unfolds into a flexible loop so that Cys92 can rapidly form a disulfide bond with the oxidized Cys44 residue.

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(current)19:44, 4 May 2022Emily Joyce (Talk | contribs)4115×1022248 KBPtGPX5 mechanism. First, Cys44 of α1-helix scavenges the peroxide, and the helix locally twists and unfolds slightly to do this. This forms the Cys44-SOH sulfenic acid intermediate. Then, α2-helix completely unfolds into a flexible loop so that Cys92 ca

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