Inositol 1,4,5-Trisphosphate Receptor

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Mouse inositol triphosphate receptor ligand-binding core complex with its ligand inositol triphosphate (PDB entry 1n4k)

3D structures of inositol 1,4,5-trisphosphate receptor

Updated on 01-March-2021

6uqk – hInsP3R III – human - Cryo EM
5x9z, 5xa0 – mInsP3R I - mouse
3jrr – mInsP3R III ligand-binding suppressor domain
1xzz - mInsP3R I ligand-binding suppressor domain
1n4k - mInsP3R I receptor-binding core + IP3
5gug, 5xa1 – mInsP3R I + IP3
3t8s, 3uj4 - rInsP3R I ligand-binding domain - rat
3uj0 - rInsP3R I ligand-binding domain + IP3
3jav, 6mu2 – rInsP3R I – Cryo EM
6mu1 – rInsP3R I + adenophostin – Cryo EM

References

  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 1.14 1.15 1.16 1.17 1.18 Bosanac I, Alattia JR, Mal TK, Chan J, Talarico S, Tong FK, Tong KI, Yoshikawa F, Furuichi T, Iwai M, Michikawa T, Mikoshiba K, Ikura M. Structure of the inositol 1,4,5-trisphosphate receptor binding core in complex with its ligand. Nature. 2002 Dec 12;420(6916):696-700. Epub 2002 Nov 17. PMID:12442173 doi:10.1038/nature01268
  2. 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 2.12 2.13 2.14 2.15 Patel S, Joseph SK, Thomas AP. Molecular properties of inositol 1,4,5-trisphosphate receptors. Cell Calcium. 1999 Mar;25(3):247-64. PMID:10378086 doi:10.1054/ceca.1999.0021

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