Interferon regulatory factor

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Structure of mouse interferon regulatory factor DNA-binding domain dimer complex with DNA (PDB entry 1if1)

3D structures of interferon regulatory factor

Updated on 05-October-2021


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  3. Weaver BK, Kumar KP, Reich NC. Interferon regulatory factor 3 and CREB-binding protein/p300 are subunits of double-stranded RNA-activated transcription factor DRAF1. Mol Cell Biol. 1998 Mar;18(3):1359-68. PMID:9488451
  4. Raczkowski F, Ritter J, Heesch K, Schumacher V, Guralnik A, Hocker L, Raifer H, Klein M, Bopp T, Harb H, Kesper DA, Pfefferle PI, Grusdat M, Lang PA, Mittrucker HW, Huber M. The transcription factor Interferon Regulatory Factor 4 is required for the generation of protective effector CD8+ T cells. Proc Natl Acad Sci U S A. 2013 Sep 10;110(37):15019-24. doi:, 10.1073/pnas.1309378110. Epub 2013 Aug 26. PMID:23980171 doi:
  5. Suprunenko T, Hofer MJ. The emerging role of interferon regulatory factor 9 in the antiviral host response and beyond. Cytokine Growth Factor Rev. 2016 Jun;29:35-43. doi:, 10.1016/j.cytogfr.2016.03.002. Epub 2016 Mar 4. PMID:26987614 doi:
  6. Barnes B, Lubyova B, Pitha PM. On the role of IRF in host defense. J Interferon Cytokine Res. 2002 Jan;22(1):59-71. PMID:11846976 doi:
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