Function
Methane monooxygenase or Methane monooxygenase hydroxylase (MMO) catalyzes the oxidation of the C-H bond of methane and other alkanes. MMO catalyzes the conversion of CH4 and O2 to CH3OH and H2O using NADPH as reducing agent. The soluble MMO (sMMO) has Fe-O-Fe in its active site[1] while the particulate MMO (pMMO) has Cu in it[2]. MMO is composed of 3 subunits.
- Subunit α is the hydroxylase (MMOH) and contains the di-iron active site.
- Subunit β is a reductase which contains the co-factors FAD and 2Fe-2S complex.
- Subunit γ is regulatory (MMOR) and is involved in coupling.
MMO is found in methanotropic bacteria.
Methane monooxygenase 3D structures
Methane monooxygenase 3D structures
