Mitogen-activated protein kinase kinase kinase kinase 1

From Proteopedia

References

1. ↑ He TS, Huang J, Chen T, Zhang Z, Cai K, Yu J, Xu LG. The Kinase MAP4K1 Inhibits Cytosolic RNA-Induced Antiviral Signaling by Promoting Proteasomal Degradation of TBK1/IKKε. Microbiol Spectr. 2021 Dec 22;9(3):e0145821. PMID:34908452 doi:10.1128/Spectrum.01458-21
2. ↑ Ling Q, Li F, Zhang X, Mao S, Lin X, Pan J, Ye W, Wei W, Qian Y, Hu C, Huang X, Wang J, Wang H, Huang J, Wang Y, Jin J. MAP4K1 functions as a tumor promotor and drug mediator for AML via modulation of DNA damage/repair system and MAPK pathway. EBioMedicine. 2021 Jul;69:103441. PMID:34166980 doi:10.1016/j.ebiom.2021.103441
3. ↑ Sawasdikosol S, Zha R, Yang B, Burakoff S. HPK1 as a novel target for cancer immunotherapy. Immunol Res. 2012 Dec;54(1-3):262-5. PMID:22477524 doi:10.1007/s12026-012-8319-1
4. ↑ Johnson E, McTigue M, Gallego RA, Johnson TW, Timofeevski S, Maestre M, Fisher TS, Kania R, Sawasdikosol S, Burakoff S, Cronin CN. Multiple conformational states of the HPK1 kinase domain in complex with sunitinib reveal the structural changes accompanying HPK1 trans-regulation. J Biol Chem. 2019 Apr 24. pii: AC119.007466. doi: 10.1074/jbc.AC119.007466. PMID:31018963 doi:http://dx.doi.org/10.1074/jbc.AC119.007466