Montelukast

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Cytochrome P450 2C8 in Humans complexed with Montelukast (PDB code 2nni)

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References

  1. Bentli, R., Ciftci, O., Cetin, A., and Otlu, A. (2016) Anti-inflammatory Montelukast prevents toxic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin: Oxidative stress, histological alterations in liver, and serum cytokine levels. Toxicology and Industrial Health, 32(5), 769-776. doi: 10.1177/0748233713505894
  2. Cylllyl, A., Kara, A., O­zdemir, T., Ogus, C. , and Gulkesen K. (2003) Effects of oral montelukast on airway function in acute asthma. Respiratory Medicine, 97(5), 533-536. doi: 10.1053/rmed.2003.1479
  3. 3.0 3.1 Nayak, A. (2004). A review of montelukast in the treatment of asthma and allergic rhinitis. Expert Opinion on Pharmacotherapy, 5:3, 679-686. doi:10.1517/14656566.5.3.679
  4. Paggiaro, P., Bacci, E. (2011) Montelukast in Asthma: A Review of its Efficacy and Place in Therapy. Therapeutic Advances in Chronic Disease, 2(1), 47-58. doi: 10.1177/ 2040622310383343
  5. https://www3.rcsb.org/ligand/MTK
  6. http://www.uniprot.org/uniprot/Q9Y271#sequences
  7. http://www.rcsb.org/pdb/protein/Q9Y271
  8. Bandaru, S., Marri, V. K., Kasera, P., Kovuri, P., Girdhar, A., Mittal, D. R., . . . Nayarisseri, A. (2014). Structure based virtual screening of ligands to identify cysteinyl leukotriene receptor 1 antagonist. Bioinformation, 10(10), 652-657. doi:10.6026/97320630010652
  9. http://www.uniprot.org/uniprot/P10632#sequences
  10. Kabsch, W., & Sander, C. (1983, December). Dictionary of protein secondary structure: Pattern recognition of hydrogen-bonded and geometrical features. Biopolymers, 22(12), 2577-2637. doi:10.1002/bip.360221211
  11. http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nni
  12. 12.0 12.1 12.2 2NNI_MTK.png
  13. Diamant, Z., Mantzouranis, E., & Bjermer, L. (2009). Montelukast in the treatment of asthma and beyond. Expert Reviews, 5, 639-658. doi:10.1586/eci.09.62
  14. 14.0 14.1 14.2 Drazen, J., Elliot, I., & O’Byrne, P. (1999). Treatment of Asthma with Drugs Modifying the Leukotriene Pathway. The New England Journal of Medicine, 340, 197-206. doi:10.1056/NEJM199901213400306
  15. 15.0 15.1 15.2 15.3 Wenzel, S.E. (1997). Arachidonic Acid Metabolites: Mediators of Inflammation in Asthma. Pharmacotherapy, 17, 3S-12S. doi:10.1002/j.1875-9114.1997tbo3696.x
  16. 16.0 16.1 Tintinger, G., Feldman, C., Theron, A., and Anderson, R. (2010) Montelukast:more than a cysteinyl leukotriene receptor antagonist? The Scientific World Journal, 10, 2403-2413. doi:10.1100/tsw.2010.229.

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