Mu Opioid Receptor

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Mu Opioid Receptor

Chimera of human Delta Opioid 7TM Receptor and E. coli cytochrome B562 in complex with oleate, tartrate, naltrindole, oleate derivative and Na+ ion (PDB code 4n6h)

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  1. 1.0 1.1 1.2 Pasternak GW, Pan YX. Mu opioids and their receptors: evolution of a concept. Pharmacol Rev. 2013 Sep 27;65(4):1257-317. doi: 10.1124/pr.112.007138. Print, 2013. PMID:24076545 doi:
  2. 2.0 2.1 Serohijos AW, Yin S, Ding F, Gauthier J, Gibson DG, Maixner W, Dokholyan NV, Diatchenko L. Structural basis for mu-opioid receptor binding and activation. Structure. 2011 Nov 9;19(11):1683-90. doi: 10.1016/j.str.2011.08.003. PMID:22078567 doi:
  3. Matthes HW, Maldonado R, Simonin F, Valverde O, Slowe S, Kitchen I, Befort K, Dierich A, Le Meur M, Dolle P, Tzavara E, Hanoune J, Roques BP, Kieffer BL. Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene. Nature. 1996 Oct 31;383(6603):819-23. doi: 10.1038/383819a0. PMID:8893006 doi:
  4. National Institute on Drug Abuse. “Opioid Overdose Crisis.” NIDA, 6 Mar. 2018,
  5. Pasternak G, Pan YX. Mu opioid receptors in pain management. Acta Anaesthesiol Taiwan. 2011 Mar;49(1):21-5. doi: 10.1016/j.aat.2010.12.008., Epub 2011 Mar 17. PMID:21453899 doi:
  6. Contet, Candice, et al. “Mu Opioid Receptor: a Gateway to Drug Addiction.” Current Opinion in Neurobiology, 19 May 2004, pp. 370–378., doi:10.1016/s0959-4388(04)00072-8.

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