Muscarinic acetylcholine receptor

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Human muscarinic acetylcholine receptor M2 complex with antagonist (PDB code 5zkb)

3D Structures of muscarinic acetylcholine receptors

Updated on 03-June-2021

References

  1. Ishii M, Kurachi Y. Muscarinic acetylcholine receptors. Curr Pharm Des. 2006;12(28):3573-81. doi: 10.2174/138161206778522056. PMID:17073660 doi:http://dx.doi.org/10.2174/138161206778522056
  2. Ockenga W, Kuhne S, Bocksberger S, Banning A, Tikkanen R. Non-neuronal functions of the m2 muscarinic acetylcholine receptor. Genes (Basel). 2013 Apr 2;4(2):171-97. doi: 10.3390/genes4020171. PMID:24705159 doi:http://dx.doi.org/10.3390/genes4020171
  3. Jiang S, Li Y, Zhang C, Zhao Y, Bu G, Xu H, Zhang YW. M1 muscarinic acetylcholine receptor in Alzheimer's disease. Neurosci Bull. 2014 Apr;30(2):295-307. doi: 10.1007/s12264-013-1406-z. Epub 2014 , Mar 3. PMID:24590577 doi:http://dx.doi.org/10.1007/s12264-013-1406-z
  4. Eglen RM. Muscarinic receptor subtype pharmacology and physiology. Prog Med Chem. 2005;43:105-36. doi: 10.1016/S0079-6468(05)43004-0. PMID:15850824 doi:http://dx.doi.org/10.1016/S0079-6468(05)43004-0
  5. Suno R, Lee S, Maeda S, Yasuda S, Yamashita K, Hirata K, Horita S, Tawaramoto MS, Tsujimoto H, Murata T, Kinoshita M, Yamamoto M, Kobilka BK, Vaidehi N, Iwata S, Kobayashi T. Structural insights into the subtype-selective antagonist binding to the M2 muscarinic receptor. Nat Chem Biol. 2018 Dec;14(12):1150-1158. doi: 10.1038/s41589-018-0152-y. Epub, 2018 Nov 12. PMID:30420692 doi:http://dx.doi.org/10.1038/s41589-018-0152-y

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