Best example is PDB entry 3wja and is shown in the viewer.
Catalytic Activity
Oxaloacetate = pyruvate + CO(2).Data source: Uniprot P48163
Or the decarboxylation of malate to pyruvate[1].
Biological process
Is involved in the following biological processes:
malate metabolic process
oxidation-reduction process
response to carbohydrate
response to hormone
carbohydrate metabolic process
protein tetramerization
regulation of NADP metabolic process
NADP biosynthetic process
small molecule metabolic process
cellular lipid metabolic process
In structures
NADP-dependent malic enzyme is found in 3 PDB entries
- Eukaryota (3 PDB entries):
- Homo sapiens (2 PDB entries):
- Columba livia (1 PDB entries):
- 1gq2
- Title: MALIC ENZYME FROM PIGEON LIVER
- 2.5 A resolution
Alternative names for NADP-dependent malic enzyme
Molecule NADP-dependent malic enzyme, also known as NADP-ME, NADP-dependent malic enzyme and Malic enzyme 1.
3D Structures of NADP-dependent malic enzyme
Updated on 11-July-2023
3wja, 2aw5 – hME - human
7x11, 7x12 – hME1 + NADP
8e76, 8eyn – hME3
8e78, 8e8o, 8eyo – hME3 + NADP
1gq2 – ME + NADP - pigeon
5ou5 – ME - maize
References
- ↑ Loeber G, Dworkin MB, Infante A, Ahorn H. Characterization of cytosolic malic enzyme in human tumor cells. FEBS Lett. 1994 May 16;344(2-3):181-6. PMID:8187880