PISA

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Protein interfaces, surfaces and assemblies service PISA at European Bioinformatics Institute http://www.ebi.ac.uk/msd-srv/prot_int/pistart.html, authored by E. Krissinel and K. Henrick. Quoting from the PISA website: "PISA is an interactive tool for the exploration of macromolecular (protein, DNA/RNA and ligand) interfaces, prediction of probable quaternary structures (assemblies), database searches of structurally similar interfaces and assemblies, as well as searches on various assembly and PDB entry parameters."[1] PISA is a core part of CCP4.[2]


Biological units displayed in the 'Structure Box' on Proteopedia PDB entry pages (e.g. 1h88) are predictions of the most likely biological unit as calculated by PISA, as well as all biological unit structures natively available in Proteopedia (i.e. those that were not uploaded by Proteopedia users).

References

  1. Krissinel E, Henrick K. Inference of macromolecular assemblies from crystalline state. J Mol Biol. 2007 Sep 21;372(3):774-97. Epub 2007 May 13. PMID:17681537 doi:10.1016/j.jmb.2007.05.022
  2. . The CCP4 suite: programs for protein crystallography. Acta Crystallogr D Biol Crystallogr. 1994 Sep 1;50(Pt 5):760-3. PMID:15299374 doi:10.1107/S0907444994003112

Proteopedia Page Contributors and Editors (what is this?)

Eran Hodis

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