Phosphoserine phosphatase

spinqualitylabelsall models Human phosphoserine phosphatase dimer complex with serine and phosphate 1l8o Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function Phosphoserine phosphatase (PSP) catalyzes the dephosphorylation of phosphoserine to produce serine and phosphate. This is the last reaction in serine biosynthesis. PSP is part of the glycine, serine and threonine metabolism. Mg+2 ion is a cofactor of PSP. Disease Mutations of PSP were found in patients with Williams syndrome. Structural highlights The human PSP overall structure contains a large core domain and a smaller 4-helix bundle domain. The active site is located in a cleft between the 2 domains.

3D structures of phosphoserine phosphatase

Phosphoserine phosphatase 3D structures

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