Plant defensin

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Plant defensin 1ayj
Plant defensin 1ayj

PDB ID 1ayj

Plant defensin 1ayj
Non-Standard Residues:
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml

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Petunia hybrida Flowers Produce Two Unique Plant Defensins

The flowers of petunia (Petunia hybrida) accumulate high levels of at least two defensins (PhD1 and PhD2) as part of their defense armoury against potential pathogen infection. In contrast to the well-described seed defensins (Class I), these petunia floral defensins are produced as precursors with anionic C-terminal propeptides (CTPP) in addition to a typical secretion signal peptide and central basic defensin domain (47 amino acids) (Class II). PhD1 and PhD2 isolated from petunia flowers lack the CTPP, suggesting that it is removed during or after transit through the secretory pathway. In addition to the eight canonical cysteine residues that define the plant defensin family, PhD1 and PhD2 is unique to this family in that it contains an extra pair of cysteines that form a fifth disulfide bond. Hence, Lay et al. (2003) have defined them as a new subclass of this family of proteins.

Related References

Defensins - Components of the innate immune system in plants., Lay FT, Anderson MA, Curr Protein Pept Sci. 2005 Feb;6(1):85-101. PMID:15638771 - review pointing out the salient features of Class I and Class II plant defensins

Isolation and properties of floral defensins from ornamental tobacco and petunia. Lay FT, Brugliera F, Anderson MA. Plant Physiol. 2003 Mar;131(3):1283-93. PMID:12644678 - original paper detailing the purification, expression and activity of PhD1 and PhD2

--Fung Lay

3D structures of Plant defensin
1ayj 1bk8 1gps 1gpt 1jkz 1n4n

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