Poliovirus receptor-related protein

From Proteopedia

Poliovirus receptor-related protein 1 (green) complex with herpes virus envelope glycoprotein (magenta) (PDB code 4myw) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image Function Poliovirus receptor-related protein (PVRP) or Nectin are membrane glycoproteins belonging to the immunoglobulin family. PVRP-1 mediates Ca+2-independent cell adhesion[1]. PVRP-2 and PVRP-3 are components of the adherens junction[2]. PVRP-4 binds PVRP-1. Relevance PVRP-4 is involved in tumor cell migration. Structural highlights . (PDB code 4myw)

3D structures of poliovirus receptor-related protein

Updated on 08-August-2019

References

1. ↑ Geraghty RJ, Krummenacher C, Cohen GH, Eisenberg RJ, Spear PG. Entry of alphaherpesviruses mediated by poliovirus receptor-related protein 1 and poliovirus receptor. Science. 1998 Jun 5;280(5369):1618-20. PMID:9616127
2. ↑ Lopez M, Aoubala M, Jordier F, Isnardon D, Gomez S, Dubreuil P. The human poliovirus receptor related 2 protein is a new hematopoietic/endothelial homophilic adhesion molecule. Blood. 1998 Dec 15;92(12):4602-11. PMID:9845526