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Bovine rhodopsin complex with retinal (PDB code 1jfp)

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  1. Hornak V, Ahuja S, Eilers M, Goncalves JA, Sheves M, Reeves PJ, Smith SO. Light activation of rhodopsin: insights from molecular dynamics simulations guided by solid-state NMR distance restraints. J Mol Biol. 2010 Feb 26;396(3):510-27. Epub 2009 Dec 11. PMID:20004206 doi:10.1016/j.jmb.2009.12.003
  2. 2.0 2.1 2.2 2.3 2.4 2.5 Sakmar TP. Structure of rhodopsin and the superfamily of seven-helical receptors: the same and not the same. Curr Opin Cell Biol. 2002 Apr;14(2):189-95. PMID:11891118
  3. 3.0 3.1 3.2 3.3 Kristiansen K. Molecular mechanisms of ligand binding, signaling, and regulation within the superfamily of G-protein-coupled receptors: molecular modeling and mutagenesis approaches to receptor structure and function. Pharmacol Ther. 2004 Jul;103(1):21-80. PMID:15251227 doi:10.1016/j.pharmthera.2004.05.002
  4. Millar RP, Newton CL. The year in G protein-coupled receptor research. Mol Endocrinol. 2010 Jan;24(1):261-74. Epub 2009 Dec 17. PMID:20019124 doi:10.1210/me.2009-0473
  5. 5.0 5.1 5.2 Meng EC, Bourne HR. Receptor activation: what does the rhodopsin structure tell us? Trends Pharmacol Sci. 2001 Nov;22(11):587-93. PMID:11698103
  6. 6.0 6.1 Shieh T, Han M, Sakmar TP, Smith SO. The steric trigger in rhodopsin activation. J Mol Biol. 1997 Jun 13;269(3):373-84. PMID:9199406 doi:10.1006/jmbi.1997.1035
  7. 7.0 7.1 7.2 7.3 7.4 7.5 7.6 7.7 7.8 Okada T, Ernst OP, Palczewski K, Hofmann KP. Activation of rhodopsin: new insights from structural and biochemical studies. Trends Biochem Sci. 2001 May;26(5):318-24. PMID:11343925
  8. 8.0 8.1 Okada T, Sugihara M, Bondar AN, Elstner M, Entel P, Buss V. The retinal conformation and its environment in rhodopsin in light of a new 2.2 A crystal structure. J Mol Biol. 2004 Sep 10;342(2):571-83. PMID:15327956 doi:10.1016/j.jmb.2004.07.044
  9. 9.0 9.1 Janz JM, Farrens DL. Assessing structural elements that influence Schiff base stability: mutants E113Q and D190N destabilize rhodopsin through different mechanisms. Vision Res. 2003 Dec;43(28):2991-3002. PMID:14611935
  10. 10.0 10.1 10.2 Kisselev OG. Focus on molecules: rhodopsin. Exp Eye Res. 2005 Oct;81(4):366-7. PMID:16051215 doi:10.1016/j.exer.2005.06.018
  11. 11.0 11.1 11.2 Verhoeven MA, Bovee-Geurts PH, de Groot HJ, Lugtenburg J, DeGrip WJ. Methyl substituents at the 11 or 12 position of retinal profoundly and differentially affect photochemistry and signalling activity of rhodopsin. J Mol Biol. 2006 Oct 13;363(1):98-113. Epub 2006 Jul 28. PMID:16962138 doi:10.1016/j.jmb.2006.07.039
  12. 12.0 12.1 12.2 12.3 Morris MB, Dastmalchi S, Church WB. Rhodopsin: structure, signal transduction and oligomerisation. Int J Biochem Cell Biol. 2009 Apr;41(4):721-4. Epub 2008 Aug 3. PMID:18692154 doi:10.1016/j.biocel.2008.04.025
  13. 13.0 13.1 13.2 13.3 13.4 Nelson, D., and Cox, M. Lehninger Principles of Biochemistry. 2008. 5th edition. W. H. Freeman and Company, New York, New York, USA. pp. 462-465.
  14. Hurley JB, Spencer M, Niemi GA. Rhodopsin phosphorylation and its role in photoreceptor function. Vision Res. 1998 May;38(10):1341-52. PMID:9667002
  15. 15.0 15.1 15.2 Park JH, Scheerer P, Hofmann KP, Choe HW, Ernst OP. Crystal structure of the ligand-free G-protein-coupled receptor opsin. Nature. 2008 Jul 10;454(7201):183-7. Epub 2008 Jun 18. PMID:18563085 doi:10.1038/nature07063
  16. 16.0 16.1 Surya A, Knox BE. Enhancement of opsin activity by all-trans-retinal. Exp Eye Res. 1998 May;66(5):599-603. PMID:9628807 doi:10.1006/exer.1997.0453

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