Ribosomal protein S7

From Proteopedia

Function Ribosomal protein S7 (RPS7) is one of the 22 proteins which belong to the 30S small subunit of the bacterial ribosome or the 30 proteins which belong to the 40S small subunit of the eukaryotic ribosome. It binds to 16S RRNA and is one of the proteins responsible for the initiation of the 30S particle assembly. It crosslinks with tRNA at the A- and P-sites[1]. Disease Mutations in mitochondrial RPS7 cause congenital sensorineural deafness and progressive hepatic and renal failure[2].

spinqualitylabelsall models Ribosomal protein S7 (PDB code 1rss) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

3D Structures of Ribosomal protein S7

Updated on 24-December-2019

Ribosomal protein S7

1iqv – RPS7 – Pyrococcus horikoshii

1rss – TtRPS7 - Thermus thermophilus

1hus – RPS7 – Geobacillus stearothermophilus

6jmk – RPS7 - Mycobacterium tuberculosis

3gty – RPS7 + trigger factor – Thermotoga maritima

Ribosomal protein S7 in part of small ribosomal subunit

1qd7 – TtRPS7 + TtRPS4 +TtRPS6 +TtRPS5 +TtRPS8 +TtRPS15 +TtRPS17 +TtRPS20 +16S RRNA fragment

1x18 - TtRPS7+ TtRPS2 +TtRPS11 +TtRPS18 + RNA + GTP-binding protein – Cryo EM

1dv4 – GsRPS7+TtRPS5+16S RRNA

References

1. ↑ Dean D, Yates JL, Nomura M. Identification of ribosomal protein S7 as a repressor of translation within the str operon of E. coli. Cell. 1981 May;24(2):413-9. PMID:7016341
2. ↑ Menezes MJ, Guo Y, Zhang J, Riley LG, Cooper ST, Thorburn DR, Li J, Dong D, Li Z, Glessner J, Davis RL, Sue CM, Alexander SI, Arbuckle S, Kirwan P, Keating BJ, Xu X, Hakonarson H, Christodoulou J. Mutation in mitochondrial ribosomal protein S7 (MRPS7) causes congenital sensorineural deafness, progressive hepatic and renal failure and lactic acidemia. Hum Mol Genet. 2015 Apr 15;24(8):2297-307. doi: 10.1093/hmg/ddu747. Epub 2015 Jan, 2. PMID:25556185 doi:http://dx.doi.org/10.1093/hmg/ddu747