Timolol

From Proteopedia

Timolol is a beta blocker medication used either by mouth or as eye drops.^[1]^[2] As eye drops it is used to treat increased pressure inside the eye such as in ocular hypertension and glaucoma.^[1] By mouth it is used for high blood pressure, chest pain due to insufficient blood flow to the heart, to prevent further complications after a heart attack, and to prevent migraines.^[2] Timolol is a non-selective beta blocker. See also Timolol, Beta-2 Adrenergic Receptor, and G-protein coupled receptors.

Beta-2 adrenergic receptor with Timolol (6ps6).

Timolol binding site.

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The Resolver thinks Mol

33624

Marvin 12300703363D

33624

pubchem_bondannotations:"1 7 8\n1 8 8\n20 21 8\n11 4 5\n7 20 8\n8 21 8"

stdinchi:"InChI=1S/C13H24N4O3S/c1-13(2,3)14-8-10(18)9-20-12-11(15-21-16-12)17-4-6-19-7-5-17/h10,14,18H,4-9H2,1-3H3/t10-/m0/s1"

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formula:"C13 H24 N4 O3 S"

mw:"316.4196"

smiles:"S1N=C(C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])OC([H])([H])[C@]([H])(C([H])([H])[N@]([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])O[H]"

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reading 45 atoms

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Time for creating model: 8 ms

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Standard Hbond calculation

0 hydrogen bonds

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Timolol

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References

↑ ^1.0 ^1.1 "Timolol eent". The American Society of Health-System Pharmacists. Archived from the original on 28 December 2016. Retrieved 8 December 2016.
↑ ^2.0 ^2.1 "Timolol Maleate". The American Society of Health-System Pharmacists. Archived from the original on 28 December 2016. Retrieved 8 December 2016.

Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Michal Harel

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Timolol

From Proteopedia

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