From Proteopedia

Anaplastic Lymphoma Kinase

spinqualitylabelsall models Structure of the Human ALK GRD Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image [1] Contents 1 Introduction 2 Structure 3 Function 4 Disease Introduction Structure Figure 1. The coolest image of this protein EVAH!!! [2] Function Disease [2] ALK-positive Lung Cancer

References

1. ↑ Li T, Stayrook SE, Tsutsui Y, Zhang J, Wang Y, Li H, Proffitt A, Krimmer SG, Ahmed M, Belliveau O, Walker IX, Mudumbi KC, Suzuki Y, Lax I, Alvarado D, Lemmon MA, Schlessinger J, Klein DE. Structural basis for ligand reception by anaplastic lymphoma kinase. Nature. 2021 Dec;600(7887):148-152. doi: 10.1038/s41586-021-04141-7. Epub 2021, Nov 24. PMID:34819665 doi:http://dx.doi.org/10.1038/s41586-021-04141-7
2. ↑ ^{2.0 2.1} Ransey E, Paredes E, Dey SK, Das SR, Heroux A, Macbeth MR. Crystal structure of the Entamoeba histolytica RNA lariat debranching enzyme EhDbr1 reveals a catalytic Zn(2+) /Mn(2+) heterobinucleation. FEBS Lett. 2017 Jul;591(13):2003-2010. doi: 10.1002/1873-3468.12677. Epub 2017, Jun 14. PMID:28504306 doi:http://dx.doi.org/10.1002/1873-3468.12677

Student Contributors

• Kaylin Todor