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User:Makenna Marcinek/Sandbox 1

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GLP-1R Homo Sapien

An overview of the entire GLP-1 protein as a spinning cartoon. GLP-1 is shown in green, the GLP-1 receptor in turquoise, and the G-alpha, G-beta, and G-gamma subunits shown in pink, orange, and red respectively. PDB: 6X18

Drag the structure with the mouse to rotate

References

  1. ↑ Zhang X, Belousoff MJ, Zhao P, Kooistra AJ, Truong TT, Ang SY, Underwood CR, Egebjerg T, Šenel P, Stewart GD, Liang YL, Glukhova A, Venugopal H, Christopoulos A, Furness SGB, Miller LJ, Reedtz-Runge S, Langmead CJ, Gloriam DE, Danev R, Sexton PM, Wootten D. Differential GLP-1R Binding and Activation by Peptide and Non-peptide Agonists. Mol Cell. 2020 Nov 5;80(3):485-500.e7. PMID:33027691 doi:10.1016/j.molcel.2020.09.020
  2. ↑ Ransey E, Paredes E, Dey SK, Das SR, Heroux A, Macbeth MR. Crystal structure of the Entamoeba histolytica RNA lariat debranching enzyme EhDbr1 reveals a catalytic Zn(2+) /Mn(2+) heterobinucleation. FEBS Lett. 2017 Jul;591(13):2003-2010. doi: 10.1002/1873-3468.12677. Epub 2017, Jun 14. PMID:28504306 doi:http://dx.doi.org/10.1002/1873-3468.12677

Student Contributors

  • Makenna Marcinek
  • Isabel Kluszynski

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Makenna Marcinek

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